Blue rubber bleb nevus syndrome (BRBNS) is a rare condition that occurs when blood vessels develop abnormally in different regions of the body, affecting the skin, soft tissue, and intestinal tract.
Vascular malformations associated with blue rubber bleb nevus syndrome
Individuals with blue rubber bleb nevus syndrome have visible venous malformations on the skin. These lesions appear blue and feel hard or rubbery to the touch; they may also extend deeper into soft tissue and internal organs. In particular, patients with BRBNS develop lesions in the gastrointestinal tract -- often in the small or large intestine.