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The University of Chicago Medicine - Comer Children's Hospital

Childhood Lymphoma Treatment

The University of Chicago Medicine Comer Children’s Hospital provides the full range of diagnostic, treatment and long-term follow-up care for children and adolescents with lymphoma.


The diagnosis of lymphoma begins with a complete medical history and exam. If lymphoma is suspected, some of the following tests may be performed to establish a diagnosis:

  • Biopsy of lymph nodes or of the mass (by minimally invasive surgery, open surgery or interventional radiology) to assess if your child has lymphoma
  • Pathology (microscopic examination of tissue) to determine the type of lymphoma
  • Bone marrow aspirate or biopsy and medical imaging (X-ray, MRI, CT, PET and/or bone scans) to determine extent of the disease
  • Blood and urine tests

Advanced Treatments

When choosing a course of treatment, our hematologist/oncologists do everything possible to minimize the effects of therapy on a child's health and development. In addition to conventional treatments, we provide the latest therapies for lymphoma including:

  • The most recent approaches to chemotherapy, including the newest targeted agents.
  • The most advanced radiation therapy, which focuses on cancer cells, avoiding harm to healthy cells and tissue.
  • Blood stem cell and bone marrow transplantation
  • Combined modalities of surgery, chemotherapy and radiation when needed
  • Advanced supportive therapies to reduce fatigue, infections, bleeding, nausea and other side effects of treatment
  • Clinical trials of promising new therapies

Our doctors and researchers continue to look for ways to refine treatments so that patients get the most effective therapy with the least toxicity.

Care for a Lifetime

Children facing cancer often have ongoing medical, emotional, social and developmental needs. Our doctors, nurses and other healthcare professionals recognize these issues and provide resources and tools to help patients and families cope and stay informed.

While most lymphoma patients are cured, some may face other complex health problems as they grow older. The University of Chicago Childhood Cancer Survivors Center is an integrated program aimed at the prevention and treatment of long-term health issues associated with cancer therapy.