"We believe CAR T will be a foundation for other therapies that eradicate cancer."
-- John M. Cunningham, MD
CAR T-cell therapy does present a risk of serious, potentially life-threatening side effects, which include high fever, flu-like symptoms, infections and low blood pressure. The FDA requires special certification for all sites offering the treatment to confirm the institution is well suited to handle serious adverse reactions, should they occur.
On August 30, 2017, the Food and Drug Administration approved CAR T-cell therapy as a treatment for advanced pediatric ALL. Comer Children’s is the only pediatric hospital in the Chicago region certified to offer CAR T-cell therapy.
"We are thrilled to offer CAR T-cell therapy to children in the Chicago area," said John M. Cunningham, MD, Comer Children’s Hospital physician-in-chief and director of the pediatric cellular therapy program. "It changes the face of treatment for pediatric ALL. And we believe CAR-T will be a foundation for other therapies that eradicate cancer."